Title:
新規な2-アミノ-イミダゾール-4-オン化合物、並びに認知障害、アルツハイマー病、神経変性及び認知症の治療に使用する医薬の製造におけるその使用
Document Type and Number:
Japanese Patent JP2009519221
Kind Code:
A
Abstract:
This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.
Inventors:
Stefan Bellui
Jeremy Burroughs
Gianni Cesari
Miles Stuart Congreve
Johann Hedström
Sven Helberg
Katharina Hegdin
Jacob Kielström
Carlin Cormodin
Johann Lindstrom
Christopher Murray
Thurhill Patel
Jeremy Burroughs
Gianni Cesari
Miles Stuart Congreve
Johann Hedström
Sven Helberg
Katharina Hegdin
Jacob Kielström
Carlin Cormodin
Johann Lindstrom
Christopher Murray
Thurhill Patel
Application Number:
JP2008541117A
Publication Date:
May 14, 2009
Filing Date:
November 20, 2006
Export Citation:
Assignee:
ASTRAZENECA AKTIEBOLAG
ASTEX THERAPEUTICS LIMITED
ASTEX THERAPEUTICS LIMITED
International Classes:
C07D233/88; A61K31/4174; A61K31/4178; A61K31/427; A61K31/4439; A61K31/4709; A61K31/4725; A61K31/497; A61K31/506; A61K31/5377; A61K31/538; A61K45/00; A61P7/04; A61P25/00; A61P25/16; A61P25/28; A61P43/00; C07C13/48; C07C25/22; C07C25/24; C07C39/373; C07C43/192; C07C43/225; C07C43/285; C07C43/295; C07C49/792; C07C49/83; C07C49/84; C07D209/12; C07D209/44; C07D215/12; C07D215/14; C07D217/06; C07D233/86; C07D265/36; C07D307/79; C07D311/04; C07D311/76; C07D339/08; C07D401/04; C07D401/10; C07D403/10; C07D405/04; C07D405/10; C07D405/14; C07D409/06; C07D409/10; C07D413/04; C07D413/08; C07D413/10; C07D417/04; C07F5/04; C07F7/08; C07F7/18; A61P9/10; A61P17/14; A61P25/14; A61P25/18; A61P25/22; A61P25/24
Foreign References:
| WO2005058311A1 | 2005-06-30 |
Attorney, Agent or Firm:
Junji Yuda
Shoji Miwa
Noriyuki Takebayashi
Chika Takagi
Shoji Miwa
Noriyuki Takebayashi
Chika Takagi