Title:
ヤーヌスキナーゼ阻害剤化合物および方法
Document Type and Number:
Japanese Patent JP5763057
Kind Code:
B2
Abstract:
The invention provides compounds of Formula I, stereoisomers or pharmaceutically acceptable salts thereof, wherein A, B, D, R1, R2, R4 and R5 are defined herein, a pharmaceutical composition that includes a compound of Formula I and methods of use thereof.
Inventors:
Goodday Car, Simon Charles
Rye, Enge
Ryan, Jun
Stephen Earl, Magnuson
Robage, Kirk Dee
Stanley, Mark S
Tsui, Vicky Shao-Way
Karen Williams
Jahn, Belong
Joe, Ahee
Rye, Enge
Ryan, Jun
Stephen Earl, Magnuson
Robage, Kirk Dee
Stanley, Mark S
Tsui, Vicky Shao-Way
Karen Williams
Jahn, Belong
Joe, Ahee
Application Number:
JP2012514472A
Publication Date:
August 12, 2015
Filing Date:
June 10, 2010
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
A61K31/44; C07D213/75; A61K31/4402; A61K31/4409; A61K31/4427; A61K31/443; A61K31/4436; A61K31/4439; A61K31/444; A61K31/4545; A61K31/4709; A61K31/496; A61K31/497; A61K31/501; A61K31/505; A61K31/506; A61K31/5377; A61K31/541; A61K31/551; A61P1/04; A61P17/06; A61P29/00; A61P35/00; A61P37/06; A61P37/08; A61P43/00; C07D213/81; C07D237/20; C07D401/12; C07D401/14; C07D405/12; C07D405/14; C07D409/12; C07D413/12; C07D413/14; C07D417/12
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| US20020183371 | ||||
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Other References:
FINK,D.M. et al,Tetrahedron Letters,1996年,Vol.37, No.7,p.995-998
ASANO,T. et al,Bioorganic & Medicinal Chemistry Letters,2004年,Vol.14,p.2299-2302
WHITE.G.A.,Pesticide Biochemistry and Physiology,1987年,Vol.27,p.249-260
PARK,Y.T. et al,Journal of Organic Chemistry,2001年,Vol.66,p.2197-2206
ASANO,T. et al,Bioorganic & Medicinal Chemistry Letters,2004年,Vol.14,p.2299-2302
WHITE.G.A.,Pesticide Biochemistry and Physiology,1987年,Vol.27,p.249-260
PARK,Y.T. et al,Journal of Organic Chemistry,2001年,Vol.66,p.2197-2206
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Naoshi Nakata
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Naoshi Nakata