To provide a keratin peeling promoter that promotes the physiological skin peeling and grows healthy skin, and a pharmaceutical preparation for external use, for example, skin cosmetic or the like and a skin-whitening cosmetic that removes melanin included in old horny layers and restores beautiful and white skin by increasing the turn-over rate of the horny layer in the skin and quickly removing the old horny substance.
The keratin peeling promoter comprises the substances increasing the activity of skin aspartic acid proteinase from apricot essence, rice bran essence, carrot essence and others. In addition, a substance that increases the activity of skin chymotrypsin-like proteinase is also used in combination. A variety of skin preparations for external use and skin cosmetics include these keratin peeling promoters.
IGARASHI SHIGERU
HIROTSU SACHIYO
HARATAKE AKINORI
HIKIMA TOSHIO