Title:
キナーゼ阻害剤
Document Type and Number:
Japanese Patent JP6995774
Kind Code:
B2
Abstract:
wherein T, A, Q, Z, R4, R5a, R5b, n, r, Het1 and Rx have meanings given in the description, which compounds are useful in synthesizing compounds that have antiinflammatory activity (e.g., through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes; Syk kinase; and members of the Src family of tyrosine kinases) and have use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.
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Inventors:
Fife, Matthew Colin Saw
Tom, Stephen Malcolm
Tom, Stephen Malcolm
Application Number:
JP2018552732A
Publication Date:
February 21, 2022
Filing Date:
April 06, 2017
Export Citation:
Assignee:
Okler Acquisitions Limited
International Classes:
C07D213/74; A61K31/44; A61K31/50; A61K31/505; A61K31/66; A61K45/00; A61P1/04; A61P11/00; A61P11/02; A61P11/06; A61P17/04; A61P17/06; A61P27/02; A61P27/06; A61P27/14; A61P37/02; A61P37/08; C07D239/47; C07D401/12; C07D405/12; C07D409/12; C07D413/12
Domestic Patent References:
| JP2015524837A |
Foreign References:
| US20140296208 | ||||
| WO2014162122A1 | ||||
| WO2015092423A1 | ||||
| WO2014162121A1 | ||||
| WO2016051187A1 | ||||
| WO2014140582A1 |
Attorney, Agent or Firm:
Patent corporation ssinpat
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