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Title:
KIT CONTAINING COORDINATION COMPLEX
Document Type and Number:
Japanese Patent JPH07206884
Kind Code:
A
Abstract:

PURPOSE: To provide a kit for producing a coordination complex comprising a substd. isonitrile and a radionuclide and an isonitrile-containing aseptic vial.

CONSTITUTION: This kit is the one for producing a coordination complex comprising an isonitrile ligand represented by the formula, (CNX)R [wherein X is a 1-4C lower alkyl group and R is selected from a group consisting of COOR1 and CONR2R3 (wherein R1 is H, a pharmacologically acceptable cation or a substd. or unsubstd. 1-4C alkyl group; and R2 and R3 are each H or a substd. or unsubstd. 1-4C alkyl group and same or different)] and a radionuclide selected from a group consisting of radioactive isotopes of Tc, Ru, Co, Pt and Re. An aseptic vial contains the kit comprising a predetermined amt. of a reducing agent capable of reducing a predetermined amt. of the isonitrile ligand and a predetermined amt. of the radionuclide preliminarily selected from the radioisotopes to form the complex and the isonitrile ligand.


Inventors:
ARAN JII JIYOONZU
ARAN DEEBUISON
JIEEMUZU KURONAAJI
MAIKERU JIEI EIBURAMUSU
Application Number:
JP1994000290091
Publication Date:
August 08, 1995
Filing Date:
November 24, 1994
Export Citation:
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Assignee:
UNIV HARVARD
MASSACHUSETTS INST TECHNOLOGY
International Classes:
C07B59/00; A61K31/28; A61K31/282; A61K33/24; A61K51/00; A61K51/04; C07B31/00; C07C67/00; C07C265/04; C07C325/00; C07C395/00; C07F13/00; C07F15/00; C07F15/06; (IPC1-7): C07F13/00; A61K51/00; C07B59/00; C07F15/00; C07F15/06
Attorney, Agent or Firm:
湯浅 恭三 (外4名)