Title:
悪性腫瘍を特定するためのキット及びその使用
Document Type and Number:
Japanese Patent JP7419068
Kind Code:
B2
Abstract:
The present disclosure provides a multiplexed amplification reaction kit for identifying a subject suffering from a malignancy sensitive to treatment with an inhibitor of the Wnt signaling pathway, comprising a primer pair capable of amplifying a PTPRK(e13)-RSPO3(e2) R-Spondin gene-fusion. Also disclosed is a method of identifying sensitivity to an inhibitor of Wnt signaling in a subject suffering from a malignancy, comprising detecting the PTPRK(e13)-RSPO3(e2) R-Spondin gene-fusion with a primer pair.
Inventors:
Bon Hwa Gun
Masafumi Inoue
Veronica diamayer
Masafumi Inoue
Veronica diamayer
Application Number:
JP2019533333A
Publication Date:
January 22, 2024
Filing Date:
December 21, 2017
Export Citation:
Assignee:
Agency for Science, Technology and Research
International Classes:
C12Q1/6886; A61P35/00; C12Q1/686
Domestic Patent References:
| JP2016518328A |
Foreign References:
| WO2016191525A1 |
Other References:
Jonathan D Boone,Laboratory Investigation,2015年12月14日,96(2),249-259
B Madan,Oncogene,2015年08月10日,35,2197-2207
B. Sanchez-Vega, et al.,Journal of Molecular Diagnostics,2002年,Vol.4, No.4,p.223-229
A. Lee, et al.,PCR Methods and Applications,1995年,Vol.4,p.283-287
B Madan,Oncogene,2015年08月10日,35,2197-2207
B. Sanchez-Vega, et al.,Journal of Molecular Diagnostics,2002年,Vol.4, No.4,p.223-229
A. Lee, et al.,PCR Methods and Applications,1995年,Vol.4,p.283-287
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mihiro
Tatsuhiko Abe
Shinya Mihiro
Tatsuhiko Abe