To provide a temperature-stable labeling reagent.
A temperature-stable labeling reagent of the formula is provided, wherein R1 represents H or an alkyl, aryl or substituted aryl group; R2 represents a detectable marker or at least two detectable markers linked together by at least one multimeric structure; L is a linking arm containing a linear succession of at least two covalent bonds; n is an integer equal to 0 or 1; R3 and R4 represent independently of each other: H, NO2, Cl, Br, F, I, R2-(L)n-Y-X-, OR, SR, NR2, R, NHCOR, CONHR, COOR with R=alkyl or aryl; A is a linking arm containing at least one covalent double bond allowing conjugation of the diazo functional group with the aromatic ring; and u is an integer of 0 to 2, preferably equal to 0 or 1.
WO/1997/049667 | INHIBITORS OF OLEAMIDE HYDROLASE |
LHOMME JEAN
LAAYOUN ALI
KOTERA MITSUHARU
TREVISIOL EMMANUELLE
MENOU LIONEL
BERNAL MENDEZ ELOY
UNIV GRENOBLE 1
CT NATL DE LA RECH SCIENT
JP4494717B2 | 2010-06-30 |
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro