Title:
ランタニド錯体、調製及びその使用方法
Document Type and Number:
Japanese Patent JP4903565
Kind Code:
B2
Abstract:
Tertiary amine complexing agents (I), are new. Tertiary amine complexing agents of formula R 1>-X-C(R 2>)(R 3>)-NR 4>R 5> (I), are new. R 1>a functional group; X : a single bond, alkylene or alkenylene (both optionally substituted by at least one heteroatom), or arylene; R 2>a group (A 2>) that is anionic at neutral pH, or 1-4C alkylene or alkenylene, containing at least one A 2> and optionally containing at least one heteroatom; R 3>H or 1-5C alkylene or alkenylene, optionally containing at least one heteroatom and optionally at least one A 2>; R 4>a substituent that absorbs light and can form three chelate rings with a lanthanide, and R 5>a substituent that can form three chelate rings with a lanthanide. Independent claims are also included for: (1) preparation of a lanthanide complex (A) by reacting (I) with a donor of lanthanide cations; (2) (A) prepared as above; (3) quantitative or qualitative analysis of a compound (B) by covalently binding (A), as a marker, to (B) and detecting and quantifying the labeled compound from the luminescent properties of the marker, and (4) a relaxation agent for nuclear magnetic resonance (NMR) containing (A).
Inventors:
Charbonnier, Roy
Giselle, Raymond
Weibel, Nicholas
Roda, Aldo
Guardigli, Massimo
Giselle, Raymond
Weibel, Nicholas
Roda, Aldo
Guardigli, Massimo
Application Number:
JP2006521610A
Publication Date:
March 28, 2012
Filing Date:
July 20, 2004
Export Citation:
Assignee:
Center Nacional Dou la Lucier Siyu Cyantei Fique (Say N Ale S)
International Classes:
C07D213/79; A61B5/055; A61K49/00; C07D401/12; C07D401/14; C07D519/00; C07F5/00; C07F9/58; C07F17/00; C09K11/06; G01N33/58; G01R33/28
Domestic Patent References:
| JP4244085A |
Foreign References:
| WO2001046207A1 | ||||
| US5559214 | ||||
| EP0770610A1 | ||||
| US5216134 | ||||
| US5892029 | ||||
| EP0649020A1 | ||||
| WO2002059097A1 | ||||
| US20020090342 |
Attorney, Agent or Firm:
Shohei Oguri
Hironori Honda
Toshimitsu Ichikawa
Hironori Honda
Toshimitsu Ichikawa