Title:
TAFIaの阻害剤としての大環状尿素およびスルファミド誘導体
Document Type and Number:
Japanese Patent JP2011521981
Kind Code:
A
Abstract:
The invention relates to compounds of the formula (I) which are inhibitors of activated thrombin-activable fibrinolysis inhibitor. The compounds of the formula I are suitable for producing medicaments for prophylaxis, secondary prevention and treatment of one or more disorders associated with thromboses, embolisms, hypercoagulability or fibrotic changes.
Inventors:
Christopher Carls
Marc Brainstrup
Andreas Efels
Anya Grobish
Hermann Schiller
Michael Wagner
Marc Brainstrup
Andreas Efels
Anya Grobish
Hermann Schiller
Michael Wagner
Application Number:
JP2011512000A
Publication Date:
July 28, 2011
Filing Date:
May 22, 2009
Export Citation:
Assignee:
Sanofi-Aventis
International Classes:
C07D273/01; A61K31/395; A61P3/00; A61P3/10; A61P7/02; A61P9/00; A61P9/06; A61P9/10; A61P11/08; A61P19/02; A61P27/02; A61P29/00; A61P31/04; A61P35/00; A61P35/04
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Noriyuki Takebayashi