Title:
レクチン結合体
Document Type and Number:
Japanese Patent JP2006527182
Kind Code:
A
Abstract:
A conjugate includes at least one target-seeking unit, which specifically binds to receptors on the surface of endothelial cells, and at least one effector unit which is coupled to the unit by a linker. The effector unit exhibits at least one signal unit and optionally at least one therapeutic active substance. The target-seeking unit includes a lectin or a fragment or derivative thereof, wherein the lectin is not L-selectin and the signal unit includes a lanthanide ion.
Inventors:
Kepler Bernhard
De Bage Paul
Bachberger Wolfgang
De Bage Paul
Bachberger Wolfgang
Application Number:
JP2006508288A
Publication Date:
November 30, 2006
Filing Date:
June 07, 2004
Export Citation:
Assignee:
Faustus Forcesungssee. Translational Cancer Research GM Behr
International Classes:
A61K47/48; A61K38/00; A61K45/00; A61K49/00; A61K49/06; A61K49/14; A61K49/18; A61K51/08; A61P35/00; C07K2/00; C07K14/005; C07K14/195; C07K14/42; C07K14/47; C07K
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi