Title:
LEUKEMIA THERAPEUTIC AGENT, LEUKEMIA CELL GROWTH INHIBITOR, HEMATOPOIETIC STEM CELL TRANSPLANTATION PRETREATMENT AGENT, AND DETERMINING METHOD OF EFFECT
Document Type and Number:
Japanese Patent JP2015212242
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a Leukemia therapeutic agent, Leukemia cell growth inhibitor, hematopoietic stem cell transplantation pretreatment agent, and determining method of effect.SOLUTION: FASN inhibitor is useful as a leukemia therapeutic agent and the like because of an action which inhibits proliferation of leukemia cell having at least either one fusion gene of a NUP98 fusion gene, CALM fusion gene, and AF10 fusion gene. By the leukemia therapeutic agent and the like, it is useful for the treatment of leukemia which has at least either one fusion gene of a NUP98 fusion gene, CALM fusion gene, and AF10 fusion gene, or hematopoietic stem cell transplantation.
Inventors:
KITABAYASHI KAZUO
SHIMA YUTAKA
SHIMA YUTAKA
Application Number:
JP2014095467A
Publication Date:
November 26, 2015
Filing Date:
May 02, 2014
Export Citation:
Assignee:
NAT CANCER CT
International Classes:
A61K45/00; A61K31/198; A61K31/365; A61K31/675; A61K31/704; A61K31/7048; A61K31/7068; A61K31/7105; A61K31/713; A61K33/24; A61K45/06; A61P35/02; C12Q1/25; C12Q1/68