Title:
LIGAND
Document Type and Number:
Japanese Patent JP2011125342
Kind Code:
A
Abstract:
To provide a dual-specific ligand having designated binding specificity.
The dual-specific ligand includes: a first immunoglobulin variable domain having the first binding specificity; and an immunoglobulin variable domain, which is complementary or non-complementary to the first immunoglobulin variable domain, and having a second binding specificity.
Inventors:
WINTER GREG
TOMLINSON IAN
IGNATOVICH OLGA
HOLT LUCY
DE ANGELIS ELENA
JONES PHILIP
TOMLINSON IAN
IGNATOVICH OLGA
HOLT LUCY
DE ANGELIS ELENA
JONES PHILIP
Application Number:
JP2011005778A
Publication Date:
June 30, 2011
Filing Date:
January 14, 2011
Export Citation:
Assignee:
DOMANTIS LTD
International Classes:
C12N15/09; A61K39/395; A61P1/04; A61P25/00; A61P29/00; A61P35/00; C07K16/00; C07K16/18; C07K16/24; C07K16/28; C07K16/40; C07K16/42; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/13; G01N33/531; G01N33/542
Domestic Patent References:
JP2005504524A | 2005-02-17 | |||
JPH09503511A | 1997-04-08 | |||
JPH09503511A | 1997-04-08 | |||
JPH03502801A | 1991-06-27 |
Other References:
JPN6013063500; J. Biol. Chem. Vol.276, No.10, 2001, pp.7346-7350
JPN6013063500; J. Biol. Chem. Vol.276, No.10, 2001, pp.7346-7350
JPN6013063502; Bioconjugate Chem. Vol.12, 2001, pp.750-756
JPN6013063505; J. Mol. Biol. Vol.290, 1999, pp.685-698
JPN6013063508; J. Mol. Biol. Vol.310, 2001, pp.591-601
JPN6013063500; J. Biol. Chem. Vol.276, No.10, 2001, pp.7346-7350
JPN6013063502; Bioconjugate Chem. Vol.12, 2001, pp.750-756
JPN6013063505; J. Mol. Biol. Vol.290, 1999, pp.685-698
JPN6013063508; J. Mol. Biol. Vol.310, 2001, pp.591-601
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Kosemura Akiko
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Kosemura Akiko