LIGHT PROTECTIVE COMPOSITION CONTAINING SORBOHYDROXAMIC ACID AND ANTI-INFLAMMORY DRUG

Japanese Patent JPH01265017

A

PURPOSE: To obtain an optically protecting topical composition containing solvohydroxamic acid and an antiinflammatory agent and useful for protecting the skin from a harmful effect caused by irradiation of ultraviolet rays such as sunburn, premature aging induced by the sunshine without preventing a sunburn response. CONSTITUTION: This optically protecting topical composition containing solvohydroxamic acid includes (A) a safe and optically protective amount, preferably 1-20wt.%, more preferably 2-5wt.% of the solvohydroxamic acid, (B) a safe and optically protective amount, preferably 0.1-10wt.%, more preferably 0.5-2wt.% of an antiinflammatory agent such as hydrocortisone, mefenamic acid and piroxicam, especially ibuprofen, naproxen and flufenamic acid and (C) a safe and optically effective amount of topical carrier, and preferably has a lotion, cream, gel, aerosol spray, cosmetic foundation or stick lip color form. The compound is preferably applied to the skin in 0.05-0.5mg/cm<2> of the component A and 0.01-0.1mg/cm<2> of the component B from 4hr before to 30min after exposure of the skin to the ultraviolet rays.

DONARUDO RIN BISETSUTO
RANJITSUTO CHIYATAAJII

JP26701988A

October 23, 1989

October 22, 1988

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PROCTER & GAMBLE

A61K8/00; A61K8/31; A61K8/33; A61K8/34; A61K8/35; A61K8/36; A61K8/362; A61K8/365; A61K8/37; A61K8/39; A61K8/40; A61K8/41; A61K8/42; A61K8/44; A61K8/49; A61K8/67; A61K8/86; A61K8/89; A61K8/891; A61K8/92; A61K8/97; A61K8/98; A61Q1/00; A61Q1/04; A61Q1/06; A61Q1/12; A61Q5/02; A61Q17/04; A61Q19/08; C11D3/48; (IPC1-7): A61K7/42; C11D3/48

Kazuo Sato (2 outside)

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