Title:
メッセンジャーＲＮＡの送達のための脂質製剤
Document Type and Number:
Japanese Patent JP7392212
Kind Code:
B2
Abstract:
The present invention provides, among other things, methods of delivering mRNA in vivo, including administering to a subject in need of delivery a composition comprising an mRNA encoding a protein, encapsulated within a liposome such that the administering of the composition results in the expression of the protein encoded by the mRNA in vivo, wherein the liposome comprises a cationic lipid of formula I-c:or a pharmaceutically acceptable salt thereof.
Inventors:
Michael Hardt Rain
Daniel Anderson
Izo Don
Frank de rosa
Daniel Anderson
Izo Don
Frank de rosa
Application Number:
JP2022045193A
Publication Date:
December 06, 2023
Filing Date:
March 22, 2022
Export Citation:
Assignee:
Translate Bio, Incorporated
International Classes:
A61K9/127; A61K48/00; A61K31/7105; A61K47/22; A61K47/24; A61K47/28; A61K47/34
Foreign References:
| WO2013063468A1 |
Attorney, Agent or Firm:
Shusaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
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