Title:
LIPID NANOPARTICLE MRNA VACCINES
Document Type and Number:
Japanese Patent JP2023109965
Kind Code:
A
Abstract:
To provide improved cationic lipids and lipid nanoparticles for the delivery of oligonucleotides.SOLUTION: A pharmaceutical composition comprises (a) an mRNA comprising a code sequence encoding a coronavirus spike (S) protein or antigen fragment thereof; and (b) a lipid nanoparticle carrier, the lipid nanoparticle carrier comprising a specific cationic lipid.SELECTED DRAWING: Figure 1A
Inventors:
PATRICK BAUMHOF
MARIOLA FOTIN-MLECZEK
REGINA HEIDENREICH
MICHAEL J HOPE
EDITH JASNY
SANDRA LAZZARO
PAULO JIA CHING LIN
JOHANNES LUTZ
BARBARA MUI
BENJAMIN PETSCH
SUSANNE RAUCH
KIM ELLEN SCHMIDT
YING TAM
MARIOLA FOTIN-MLECZEK
REGINA HEIDENREICH
MICHAEL J HOPE
EDITH JASNY
SANDRA LAZZARO
PAULO JIA CHING LIN
JOHANNES LUTZ
BARBARA MUI
BENJAMIN PETSCH
SUSANNE RAUCH
KIM ELLEN SCHMIDT
YING TAM
Application Number:
JP2023087323A
Publication Date:
August 08, 2023
Filing Date:
May 26, 2023
Export Citation:
Assignee:
CUREVAC SE
ACUITAS THERAPEUTICS INC
ACUITAS THERAPEUTICS INC
International Classes:
A61K31/7105; A61K9/14; A61K9/51; A61K31/712; A61K39/00; A61K39/215; A61K39/35; A61K47/18; A61K47/22; A61K47/34; A61K48/00; A61P31/14; A61P37/04; C07K14/165; C12N15/11; C12N15/50; C12N15/88
Attorney, Agent or Firm:
Kazuya Sekiguchi
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