Lipids and Lipid Compositions for Delivery of Active Drugs

Japanese Patent JP6352950

B2

This invention provides for a compound of formula (I):or a pharmaceutically acceptable salt thereof, wherein R¹-R⁴, L and X are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.

WO/2000/020376	N-ARALKYLAMINOTETRALINS AS LIGANDS FOR THE NEUROPEPTIDE Y Y5 RECEPTOR
JP3929700	New tricyclic compound

Jeremy Lee Barryza
Rohan Eric John Beckwith
Keith Baumann
Crystal byers
Tangina Fazar
Gabriel Grant Gumber
Cameron Chuck-Manly
Litesh Vanuda Suji Titikle
Chandra Vergies
One Shunshi
Laura West
Thomas The Bawa
Jiao Jin Pean

JP2015560839A

July 04, 2018

March 06, 2014

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Novartis Age

C07C217/58; A61K9/127; A61K31/7105; A61K31/713; A61K47/16; A61K47/18; A61K47/22; A61K47/24; A61K47/28; A61K47/34; C07C219/16; C07C219/22; C07D205/04; C07D295/096; C07D317/28

FUJII,S.,CHEMISTRY LETTERS,2012年,Vol.41, No.5,p.501-503
MOCHIZUKI,S. et al.,BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN,2012年,Vol.85, No.3,p.354-359
REN,T. et al.,JOURNAL OF DRUG TARGETING,ドイツ,1999年,Vol.7, No.4,p.285-292

Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Takahide Sasaki

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