Title:
活性物質の送達用の脂質および脂質組成物
Document Type and Number:
Japanese Patent JP6731912
Kind Code:
B2
Abstract:
or a pharmaceutically acceptable salt thereof, wherein RA, RB, R2 and R4 are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.
Inventors:
Beckwith, Rohan Eric, John
Brito, Lewis
Chris Christopher, Bryan, Addison
Gamber, gabriel, grant
Gear, Andrew
The Bawa, Thomas
Brito, Lewis
Chris Christopher, Bryan, Addison
Gamber, gabriel, grant
Gear, Andrew
The Bawa, Thomas
Application Number:
JP2017512684A
Publication Date:
July 29, 2020
Filing Date:
September 04, 2015
Export Citation:
Assignee:
Novartis Age
International Classes:
C07C229/12; A61K9/14; A61K31/7105; A61K31/711; A61K31/713; A61K39/12; A61K39/145; A61K47/18; A61K47/22; A61K47/28; A61K48/00; A61P31/12; A61P31/16; C07C219/16; C07D207/08; C07D211/34; C07D211/62
Foreign References:
| WO2007034812A1 | ||||
| WO2012121058A1 | ||||
| WO2012121057A1 | ||||
| WO2013089241A1 |
Other References:
AOKI, K. et al.,a disulfide bond replacement strategy enables the efficient design of artificial therapeutic peptides,Tetrahedron,2014年,vol.70, no.42,p.7774-7779
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Uetake Yukiko
Yasuhito Suzuki
Eiji Katayama
Norio Omori
Uetake Yukiko
Yasuhito Suzuki