Title:
LIPIDS AS SYNTHETIC VECTORS TO ENHANCE ANTIGEN PROCESSING AND PRESENTATION EX-VIVO IN DENDRITIC CELL THERAPY
Document Type and Number:
Japanese Patent JP2023088977
Kind Code:
A
Abstract:
To provide a composition for treating cancer.SOLUTION: The present invention provides a composition for treating cancer by inducing the in vivo expansion of adoptively transferred T-cells, the composition comprising a cationic lipid and an adoptively transferred T-cell. Preferably, the cationic lipid includes R-DOTAP, and the T-cell is a CD4+T cell or CD8+T cell.SELECTED DRAWING: None
Inventors:
FRANK BEDU-ADDO
GREG CONN
SIVA K GANDHAPUDI
MARTIN KEOUGH
ANGELA MOHS
RITU PATEL
SHWETA SINGH
MARTIN WARD
JEROLD WOODWARD
GREG CONN
SIVA K GANDHAPUDI
MARTIN KEOUGH
ANGELA MOHS
RITU PATEL
SHWETA SINGH
MARTIN WARD
JEROLD WOODWARD
Application Number:
JP2023044571A
Publication Date:
June 27, 2023
Filing Date:
March 20, 2023
Export Citation:
Assignee:
PDS BIOTECHNOLOGY CORP
International Classes:
A61K35/17; A61K39/00; A61K39/39; A61P35/00; C12N5/0783
Attorney, Agent or Firm:
Patent Attorney Corporation Isshiki International Patent Office