Title:
弱毒生ワクチン
Document Type and Number:
Japanese Patent JP5753098
Kind Code:
B2
Abstract:
The present invention relates to a bacterium attenuated by a mutation in at least one ABC transporter gene wherein the mutation renders the corresponding ABC transporter protein non-functional and wherein the attenuated bacterium persists in a subject.
Inventors:
Browning Glen Francis
Mark Ham Philip Francis
Tseng Chi-Wen
Mark Ham Philip Francis
Tseng Chi-Wen
Application Number:
JP2011550380A
Publication Date:
July 22, 2015
Filing Date:
February 17, 2010
Export Citation:
Assignee:
Australian Paul Tory Sea RC Sea Pty Limited
International Classes:
C12N1/20; A61K39/00; A61K39/02; A61K39/04; A61K39/08; A61K39/085; A61K39/10; A61K39/102; A61K39/104; A61K39/106; A61K39/108; A61K39/112; A61K39/118; A61K39/12; A61K39/17; A61K39/215; A61K39/295; A61K39/39; A61K47/02; A61K47/10; A61K47/12; A61K47/18; A61K47/22; A61K47/26; A61K47/36; A61K47/42; A61P31/04; A61P31/12; A61P37/04; C12N1/21; C12N15/09
Domestic Patent References:
| JP2004521613A |
Foreign References:
| US4000256 |
Other References:
ROSINHA, G.M.S., et al.,Infect. Immun.,2002年,70(9),pp.5036-5044
GARMORY, H.S., et al.,Infect. Immun.,2004年,72(12),pp.6757-6763
ANTONUCCI, T.K., et al.,TIBS,1985年 9月,pp.335-336
HAMZE, K., et al.,Microbiology,2009年 2月 1日,155,pp.398-412
GARMORY, H.S., et al.,Infect. Immun.,2004年,72(12),pp.6757-6763
ANTONUCCI, T.K., et al.,TIBS,1985年 9月,pp.335-336
HAMZE, K., et al.,Microbiology,2009年 2月 1日,155,pp.398-412
Attorney, Agent or Firm:
Masayuki Masabayashi
Hayashi Ichiyoshi
Hayashi Ichiyoshi