Title:
ベクターとして鳥類ヘルペスウイルスを用いた鳥類用組換え生ワクチン
Document Type and Number:
Japanese Patent JP4641024
Kind Code:
B2
Abstract:
Use of a recombinant turkey herpes virus (HVT) for production of live, recombinant avian vaccines, intended for vaccination in ovo, of day-old chicks, or of adults to protect against an avian pathogen (A), is new. Use of recombinant turkey herpes virus (HVT) for production of live, recombinant avian vaccines, intended for vaccination in ovo, of day-old chicks, or of adults, is new. The recombinant HVT includes at least one nucleic acid (I) that encodes and expresses an antigen (Ag) of (A), inserted into intergene region 1, 2 or 3 of the BamHI fragment of the HVT genome. These intergene regions correspond, in a virus having an approximately 5.8 kb sequence (reproduced) for the BamHI fragment, to positions 1213-1383; 1942-2283 or 3082-3569, respectively.
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Inventors:
Jean-Christophe Francis Audone
Michelle Joseph Marie Bubro
Raphael Jean Dartale
Carol Veronique Duina
Eliane Louise Francoise Laplace
Michel Albert Emile Riviere
Michelle Joseph Marie Bubro
Raphael Jean Dartale
Carol Veronique Duina
Eliane Louise Francoise Laplace
Michel Albert Emile Riviere
Application Number:
JP2006329245A
Publication Date:
March 02, 2011
Filing Date:
December 06, 2006
Export Citation:
Assignee:
Merial SS
International Classes:
C12N7/00; C12N15/09; A61K39/00; A61K39/245; A61K39/255; A61P31/00; A61P31/12; C07K14/055; C07K14/08; C07K14/125; C07K14/165; C12N7/01; C12N15/869; C12P21/02; A61K38/00
Domestic Patent References:
| JP6022757A | ||||
| JP2500409A | ||||
| JP8500969A | ||||
| JP62257385A | ||||
| JP5244939A | ||||
| JP2076578A |
Foreign References:
| WO1993025665A1 |
Other References:
BRADLEY,G. et al,Structure of the Marek's disease virus BamHI-H gene family: genes of putative importance for tumor induction,J Virol,1989年,Vol.63, No.6,p.2534-42
BUCKMASTER,A.E. et al,Gene sequence and mapping data from Marek's disease virus and herpesvirus of turkeys: implications for herpesvirus classification,J Gen Virol,1988年,Vol.69 , Pt 8,p.2033-42
BUCKMASTER,A.E. et al,Gene sequence and mapping data from Marek's disease virus and herpesvirus of turkeys: implications for herpesvirus classification,J Gen Virol,1988年,Vol.69 , Pt 8,p.2033-42
Attorney, Agent or Firm:
Takashi Koshiba