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Title:
肝臓がんの検出キット又はデバイス及び検出方法
Document Type and Number:
Japanese Patent JP7437714
Kind Code:
B2
Abstract:
It is intended to provide a kit or device for the detection of liver cancer and a method for detecting liver cancer. The present invention relates to a kit or device for the detection of liver cancer, comprising a nucleic acid capable of specifically binding to miRNA in a sample of a subject, and a method for detecting liver cancer, comprising measuring the miRNA in vitro.

Inventors:
Tetsushi Kondo
Hitoshi Nobumasa
Satoko Kozono
Yuko Sudo
Junpei Kawachi
Atsushi Ochiai
Motohiro Kojima
Application Number:
JP2022141357A
Publication Date:
February 26, 2024
Filing Date:
September 06, 2022
Export Citation:
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Assignee:
Toray Industries, Inc.
National Cancer Research Center
International Classes:
C12Q1/6886; C12M1/00; C12M1/34; C12N15/09; C12N15/11
Domestic Patent References:
JP2013538583A
Foreign References:
WO2011076141A1
Other References:
滝澤聡子他,DNAチップ3D-Gene(R)による網羅的血清中miRNA解析,BIO Clinica,2014年06月10日,Vol.29, No.6,pp.588-589
江口英利他,肝癌の腫瘍マーカーとしての末梢血中microRNAの有用性,日本癌治療学会誌,2011年,Vol.46,No.2,p.606 OS66-2
LI J. et al.,Expression of serum miR-221 in human hepatocellular carcinoma and its prognostic significance.,Biochem Biophys Res Commun.,2011年,Vol.406, No.1,pp.70-73
TURATO C. et al.,MicroRNAs and SerpinB3 in hepatocellular carcinoma.,Life Sci.,2014年03月,Vol.100, N0.1,pp.9-17
江藤弘二郎他,消化器がんとmicroRNA,臨床化学,2014年04月,Vol.43, No.2,pp.99-105
Attorney, Agent or Firm:
Yuusuke Hiraki
Setsu Fujita
Akiko Kosemura