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Title:
肝臓オルガノイド組成物ならびにその作製および使用方法
Document Type and Number:
Japanese Patent JP7078615
Kind Code:
B2
Abstract:
Disclosed are methods of treating or reducing the occurrence of a steatohepatitis disorder. The disorder may include, for example, NASH, parenteral nutrition associated liver disease (PNALD), or genetic forms of liver disease. The method may comprise the step of administering a composition comprising obeticholic acid to an individual in need thereof.

Inventors:
Takanori Takebe
Tadahiro Shinozawa
Kimura Masaki
Hiroyuki Koike
Application Number:
JP2019522219A
Publication Date:
May 31, 2022
Filing Date:
November 03, 2017
Export Citation:
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Assignee:
Children's Hospital Medical Center
Japan Science and Technology Agency
International Classes:
C12N5/10; C12N5/071; C12N5/0735; C12Q1/06
Foreign References:
WO2015183920A2
WO2016056999A1
WO2017048193A1
Other References:
Development, 2017, 144, 1056-1064
Attorney, Agent or Firm:
Taro Yaguchi