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Title:
眼疾患の局所的治療方法、並びに、その治療用組成物及び治療用手段
Document Type and Number:
Japanese Patent JP2006504701
Kind Code:
A
Abstract:
A method for the prevention or treatment of an eye disease, which includes topically applying to a patient in need of the treatment an aqueous ophthalmic composition which includes N-acetylcarnosine, a N-acetylcarnosine derivative or a pharmacologically acceptable salt of N-acetylcarnosine, in combination with an amount of a cellulose compound or a pharmacologically acceptable salt which is effective to increase intraocular absorption of N-acetylcarnosine or L-carnosine or a derivative of L-carnosine, such as anserine or balenine, in the aqueous humor. A hydrophilic hydrogel contact lens and an ocular polymer insert for topical application of an ophthalmic composition to the eyes of a patient is also disclosed, with the lens or insert containing N-acetylcarnosine, a N-acetylcarnosine derivative or a pharmacologically acceptable salt of N-acetylcarnosine.

Inventors:
Mark A. Babizayev
Application Number:
JP2004539362A
Publication Date:
February 09, 2006
Filing Date:
September 29, 2003
Export Citation:
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Assignee:
Mark A. Babizayev
International Classes:
A61K31/4172; A61K9/00; A61K9/06; A61K9/08; A61K31/07; A61K31/355; A61K31/4164; A61K47/10; A61K47/12; A61K47/32; A61K47/34; A61K47/38; A61P27/02; A61P43/00
Foreign References:
WO1995010294A11995-04-20
WO2002060495A12002-08-08
Attorney, Agent or Firm:
Koichi Hirota
Yoshihiro Nagare
Naoko Matsuda