To provide a low-substituted hydroxypropylcellulose powder having high bindability, good flowability and excellent disintegration, and a method for producing the same.
The method for producing the low-substituted hydroxypropylcellulose powder, having 0.05-1.0 molar substitution number per anhydrous glucose unit, insoluble in water and swellable with water, comprises a step for producing alkali cellulose by adding an aqueous solution of sodium hydroxide to pulverized pulp in 0.1-0.3 mass ratio of sodium hydroxide over anhydrous cellulose and mixing the mixture, a step for performing an etherification reaction of the resultant alkali cellulose, a step for neutralizing sodium hydroxide included in the obtained crude reaction product, followed by a cleaning step, a drying step and a pulverizing step for performing compaction-grinding.
UMEZAWA HIROSHI
| JPH07324101A | 1995-12-12 | |||
| JPH11322802A | 1999-11-26 | |||
| JP2001200001A | 2001-07-24 | |||
| JP2001199902A | 2001-07-24 | |||
| JP2000302802A | 2000-10-31 | |||
| JP2000204195A | 2000-07-25 | |||
| JP2000186101A | 2000-07-04 |
| GB1479557A | 1977-07-13 |
Arihara Koichi
Matsushima Tetsuo
Hidefumi Kawamura