Title:
増強された発光を産生するために赤外発光基質を活用するルシフェラーゼ配列
Document Type and Number:
Japanese Patent JP7058677
Kind Code:
B2
Abstract:
Provided herein are isolated polynucleotide encoding modified click beetle luciferase polypeptides that have enhanced luminescence and longer wavelength near-infrared signals. The disclosure also relates to near-infrared bioluminescence systems that include said modified click beetle luciferase polypeptides and novel luciferin derivatives, as well as methods of using said modified click beetle luciferase polypeptides and bioluminescence systems.
Inventors:
Encel Lance Pee
Hall Mary Pee
Wood Keith Vee
Wood Monica Gee
Hall Mary Pee
Wood Keith Vee
Wood Monica Gee
Application Number:
JP2020000374A
Publication Date:
April 22, 2022
Filing Date:
January 06, 2020
Export Citation:
Assignee:
Promega Corporation
International Classes:
C12N15/53; A01K67/027; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/02; C12N15/12; C12N15/62; C12N15/63; C12Q1/66; G01N21/76
Domestic Patent References:
| JP2009039129A | ||||
| JP2007006910A | ||||
| JP2011050258A |
Foreign References:
| WO2009140662A1 |
Other References:
Analytical Biochemistry (2005) Vol.345, pp.140-148
Gene (2010) Vol.452, pp.1-6
Gene (2010) Vol.452, pp.1-6
Attorney, Agent or Firm:
Shinichiro Tanaka
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori