Title:
ルミナシン類似物およびそれら用途
Document Type and Number:
Japanese Patent JP4443228
Kind Code:
B2
Abstract:
The present invention provides compounds having formula (I) (and pharmaceutically acceptable derivatives thereof): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R1-R14 and n are as defined herein.
Inventors:
Fan, frank
Johannes, Charles
Yao, Ye
Jou, Xiao Jae (Jeff)
Johannes, Charles
Yao, Ye
Jou, Xiao Jae (Jeff)
Application Number:
JP2003558000A
Publication Date:
March 31, 2010
Filing Date:
December 18, 2002
Export Citation:
Assignee:
Eisai R & D Management Co., Ltd.
International Classes:
C07D493/10; A61K31/35; A61K31/353; A61P9/00; A61P35/00; C07D305/14; C07D309/10; C07D493/04
Domestic Patent References:
| JP62294619A | ||||
| JP6228144A | ||||
| JP63022583A |
Foreign References:
| WO1999060000A1 | ||||
| WO2003006060A1 |
Other References:
SHARMA,ONCOGENE,英国,2001年 4月,V20 N17,P2068-2079
NARUSE,JOURNAL OF ANTIBIOTICS,日本,JAPAN ANTIBIOTICS RESEARCH ASSOCIATION,2000年 6月,V53 N6,P579-590
WAKABAYASHI T,JOURNAL OF ANTIBIOTICS,日本,JAPAN ANTIBIOTICS RESEARCH ASSOCIATION,2000年 6月,V53 N6,P591-596
TATSUTA K,TETRAHEDRON LETTERS,NL,ELSEVIER SCIENCE PUBLISHERS,2001年10月22日,V42 N43,P7625-7628
NARUSE,JOURNAL OF ANTIBIOTICS,日本,JAPAN ANTIBIOTICS RESEARCH ASSOCIATION,2000年 6月,V53 N6,P579-590
WAKABAYASHI T,JOURNAL OF ANTIBIOTICS,日本,JAPAN ANTIBIOTICS RESEARCH ASSOCIATION,2000年 6月,V53 N6,P591-596
TATSUTA K,TETRAHEDRON LETTERS,NL,ELSEVIER SCIENCE PUBLISHERS,2001年10月22日,V42 N43,P7625-7628
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita