Title:
LUNG CANCER MEDICINE CONTAINING SRC FAMILY TYROSINE KINASE INHIBITOR FOR INHIBITING VARIANT EGFR DOWNSTREAM SIGNAL AND UTILIZATION THEREOF
Document Type and Number:
Japanese Patent JP2007145745
Kind Code:
A
Abstract:
To provide a medicine for treating lung cancer cells without affecting the normal signal transmission route of receptor type tyrosine kinase, and to provide a method thereof.
This medicine for treating lung cancer having cancer cells expressing variant type EGFR is characterized by containing a Src family tyrosine kinase inhibitor not inhibiting a wild type EGFR tyrosine kinase activity in normal cells.
Inventors:
KUMAGAI TORU
KAWASE ICHIRO
NAGATOMO IZUMI
KAWASE ICHIRO
NAGATOMO IZUMI
Application Number:
JP2005340913A
Publication Date:
June 14, 2007
Filing Date:
November 25, 2005
Export Citation:
Assignee:
UNIV OSAKA
International Classes:
A61K45/00; A61P35/00; A61P43/00; C12Q1/02; C12Q1/48; C07K14/71; C12N15/09
Attorney, Agent or Firm:
Kenzo Hara International Patent Office