Title:
アルツハイマー病の治療のための大員環β-セクレターゼ阻害剤
Document Type and Number:
Japanese Patent JP2007502278
Kind Code:
A
Abstract:
The present invention is directed to compounds of formula I which are inhibitors of the beta-secretase enzyme and that are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the beta-secretase enzyme is involved
Inventors:
Cobain, craig
Stachel, Xieong Jei
Batka, Joseph P
Stachel, Xieong Jei
Batka, Joseph P
Application Number:
JP2006523290A
Publication Date:
February 08, 2007
Filing Date:
August 10, 2004
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
C07D225/08; A61K31/33; A61K31/395; A61K31/4427; A61P25/28; A61P43/00; C07D225/04; C07D267/22; C07D401/12; A61K
Foreign References:
| WO2003045378A1 | 2003-06-05 | |||
| US6333410B1 | 2001-12-25 | |||
| WO2003045378A1 | 2003-06-05 | |||
| US6333410B1 | 2001-12-25 |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura