Title:
大環状広域抗生物質
Document Type and Number:
Japanese Patent JP6437443
Kind Code:
B2
Abstract:
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
Inventors:
Roberts, Tucker, Kallan
Smith, peter, andrew
Higuchi, Robert, Ai.
David Campbell
Paraselli, Prasna
Smith, peter, andrew
Higuchi, Robert, Ai.
David Campbell
Paraselli, Prasna
Application Number:
JP2015544117A
Publication Date:
December 12, 2018
Filing Date:
November 20, 2013
Export Citation:
Assignee:
RQX Pharmaceuticals, Inc.
International Classes:
C07K7/56; A61K38/12; A61P31/04; A61P31/10
Foreign References:
| WO2012036907A2 | ||||
| WO2011112441A1 |
Attorney, Agent or Firm:
Kazuhiro Kiyohara