Title:
大環状化合物および治療方法
Document Type and Number:
Japanese Patent JP5756290
Kind Code:
B2
Abstract:
The instant invention describes macrocyclic compounds having therapeutic activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders, or affect cell differentiation, dedifferentiation or transdifferentiation.
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Inventors:
Ruched, Hendrick
Paul, Valerie, Jay.
Taori, Kanchan
Paul, Valerie, Jay.
Taori, Kanchan
Application Number:
JP2010524059A
Publication Date:
July 29, 2015
Filing Date:
September 09, 2008
Export Citation:
Assignee:
University of Florida Research Foundation, Incorporated
International Classes:
C07D513/18; A61K31/429; A61P17/06; A61P21/00; A61P25/00; A61P25/14; A61P25/28; A61P29/00; A61P31/12; A61P33/02; A61P35/00; A61P43/00; C12P1/04; C12P17/18
Other References:
J Am Chem Soc., JUL-2008, Vol.130, p.8455-8459
YING Y et al., Synthesis and Activity of Largazole Analogues with Linker and Macrocycle Modification, Org Lett., Vol.10, p.4021-4024, Published online 16-AUG-2008
Angew Chem Int Ed., AUG-2008, Vol.47, p.6483-6485
REN Q et al., Total Synthesis of Largazole, SYNLETT, No.15, p.2379-2383, Published online 21-AUG-2008
J Am Chem Soc., 13-FEB-2008, Vol.130, p.1806-1807
YING Y et al., Synthesis and Activity of Largazole Analogues with Linker and Macrocycle Modification, Org Lett., Vol.10, p.4021-4024, Published online 16-AUG-2008
Angew Chem Int Ed., AUG-2008, Vol.47, p.6483-6485
REN Q et al., Total Synthesis of Largazole, SYNLETT, No.15, p.2379-2383, Published online 21-AUG-2008
J Am Chem Soc., 13-FEB-2008, Vol.130, p.1806-1807
Attorney, Agent or Firm:
Ryoichi Takaoka