Title:
MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME
Document Type and Number:
Japanese Patent JP2014141507
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide macrocyclic compounds that can function as selective modulators of a ghrelin receptor (growth hormone secretagogue receptor).SOLUTION: This invention provides a compound of formula 1, or an optical isomer, enantiomer or diastereomer thereof, or a pharmacologically acceptable salt thereof.
Inventors:
HOVEYDA HAMID
FRASER GRAEME
SOPHIE BEAUCHEMIN
MARTIN BRASSARD
DAVID DRUTZ
ERIC MARSAULT
LUC OUELLET
MARK L PETERSON
WANG ZHIGANG
KAMEL BENAKLI
FRASER GRAEME
SOPHIE BEAUCHEMIN
MARTIN BRASSARD
DAVID DRUTZ
ERIC MARSAULT
LUC OUELLET
MARK L PETERSON
WANG ZHIGANG
KAMEL BENAKLI
Application Number:
JP2014056805A
Publication Date:
August 07, 2014
Filing Date:
March 19, 2014
Export Citation:
Assignee:
TRANZYME PHARMA INC
International Classes:
C07D273/00; A61K31/395; A61K31/4427; A61K31/4433; A61P1/04; A61P1/08; A61P1/12; A61P1/14; A61P1/16; A61P1/18; A61P9/00; A61P9/10; A61P11/02; A61P11/06; A61P17/06; A61P19/02; A61P25/00; A61P25/04; A61P25/16; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P29/00; A61P31/04; A61P37/08; A61P43/00; C07D413/06; C07D498/18
Foreign References:
| WO2006009645A1 | 2006-01-26 | |||
| WO2006046977A1 | 2006-05-04 | |||
| WO2006137974A2 | 2006-12-28 | |||
| WO2006009674A1 | 2006-01-26 | |||
| WO2004111077A1 | 2004-12-23 |
Other References:
JPN6013001472; Ｊ．Ｍｅｄ．Ｃｈｅｍ．，２００６，４９（２４），ｐ．７１９０-７
Attorney, Agent or Firm:
Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo
Hidefumi Kawamura
Ayako Nakamura
Satoshi Morimoto
Kyoko Tsunoda
Arihara Koichi
Matsushima Tetsuo
Hidefumi Kawamura
Ayako Nakamura
Satoshi Morimoto
Kyoko Tsunoda
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