Title:
C型肝炎ウィルスに対する活性を有する大環状ペプチド
Document Type and Number:
Japanese Patent JP4398424
Kind Code:
B2
Abstract:
Compounds of formula (I): wherein R1 is (C1-8)alkyl, (C3-7)cycloalkyl, {(C1-6)alkyl-(C3-7)cycloalkyl} or Het, which are all optionally substituted from 1 to 3 times with halo, cyano, nitro, O-(C1-6)alkyl, amido, amino or phenyl, or R1 is C6 or C10 aryl which is optionally substituted from 1 to 3 times with halo, cyano, nitro, (C1-6)alkyl, O-(C1-6)alkyl, amido, amino or phenyl; or a pharmaceutically acceptable salt thereof, useful as an inhibitor of the HCV NS3 protease.
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Inventors:
Lina Brune Monse
Bailey Murray Dee
Bailey Murray Dee
Application Number:
JP2005501488A
Publication Date:
January 13, 2010
Filing Date:
October 20, 2003
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07K5/083; A61K38/12; C07K5/08; A61K38/00; A61P31/14
Domestic Patent References:
| JP2005524632A |
Foreign References:
| WO2000059929A1 | ||||
| WO2002060926A1 |
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama