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Title:
MACROLIDE ANTIBIOTIC FOR EXTERMINATION OF PARASITE
Document Type and Number:
Japanese Patent JPH01272588
Kind Code:
A
Abstract:

NEW MATERIAL: A compound of the formula [wherein R is H or CH3; R1 is H, OH, COCOH(CH3)2, OCOCH(CH3)CH2CH3; R2 is H or OH; and R3 is H or OCOCH(CH3)2].

USE: A treating or a preventive agent against the infection of humans or animals with parasites, including an insecticidal, acaricidal, anthelminthic or exoparasite- exterminating composition.

PREPARATION: Streptomyces. hygroscopicus SP ATCC53718 or mutant, genetically transformed species or recombinant thereof having the ability of produce at least one N787-182 antibiotic are cultured in a deep culture aqueous medium containing utilizable carbon and nitrogen sources and inorganic salts or in a solid agar medium under deep aerobic fermentation conditions.


Inventors:
DEEBUITSUDO OOSUTEN PERII
MAAKU ANDORIYUU HAKUSERU
MAEDA HIROSHI
TONE ATSUSUKE
Application Number:
JP4501089A
Publication Date:
October 31, 1989
Filing Date:
February 23, 1989
Export Citation:
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Assignee:
PFIZER LTD
International Classes:
A01N43/90; A01N63/02; A61K31/365; A61K31/37; A61P33/00; A61P33/10; C07D493/22; C07H9/02; C07H19/01; C12N1/20; C12P17/18; C12P19/44; C12R1/55; (IPC1-7): A61K31/37; C07D493/22; C07H9/02; C12N1/20; C12P17/18
Domestic Patent References:
JPH02138187A1990-05-28
Attorney, Agent or Firm:
Kyozo Yuasa (4 outside)