MAILLARD REACTION SUPPRESSOR, COSMETIC, FOOD ADDITIVE AND FOOD

Japanese Patent JPH09315960

A

To obtain a Maillard reaction suppressor, capable of exhibiting Maillard reaction-inhibiting activity and having high safety by compounding a kind of cyclic α-hydroxyketone compound.

This Maillard reaction suppressor contains a compound of the formula [X is O, C(O) or CH=CH; R1 to R3 are each H, OH, a 1-3C hydroxyalkyl or a 1-3C alkyl], concretely at least one kind selected from a group consisting of maltol, tropolone, tetrahydroxy-1,4benzoquinone and 2,5- dihydroxy-1,4-benzoquinone as an active component. The Maillard reaction suppressor is useful for the beautification of the skin, and the prevention and prophylaxis of the senile change of the skin. Further, the suppressor is useful for the treatment and prophylaxis of arteriosclerosis, cataract, etc., attributable to various kinds of diabetic complications and senile changes. The suppressor can be formulated into an oral or parenteral preparation. Furthermore, the suppressor can be used as a component of a cosmetic such as a cream, a milky lotion or a lotion, a food or a food additive.

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MIZUNO TAKASHI
HAZAMA KAZUHIKO
UCHINO KEIJIRO
MIYASHITA RUMIKO

JP13522596A

December 09, 1997

May 29, 1996

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NIPPON FLOUR MILLS

A23L1/30; A61K8/00; A61K8/30; A61K8/35; A61K8/49; A61K31/12; A61K31/122; A61K31/35; A61K31/351; A61P9/10; A61P17/00; A61P27/02; A61P27/12; A61P43/00; A61Q19/00; A61Q19/02; A61Q19/08; C07C49/717; C07C50/04; C07D309/40; C09K3/00; (IPC1-7): A61K31/12; A23L1/30; A61K7/00; A61K7/48; A61K31/12; A61K31/35; C07C49/717; C07C50/04; C07D309/40; C09K3/00

JPH05308916A	1993-11-22
JPH0558860A	1993-03-09
JPH03161441A	1991-07-11
JPS59157009A	1984-09-06
JPS6333313A	1988-02-13
JPH06192089A	1994-07-12
JPS5089549A	1975-07-18
JPH05310565A	1993-11-22
JPH07109215A	1995-04-25
JPH06336430A	1994-12-06

US5470873A	1995-11-28
US5298525A	1994-03-29

BIOORGANIC & MEDICINAL CHEMISTRY, vol. 4, no. 1, JPN4006022732, January 1996 (1996-01-01), pages 49 - 53, ISSN: 0000790745
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BULLETIN OF TOKYO GAKUGEI UNIVERSITY SER.IV, vol. 32, JPN4006022737, 1980, pages 121 - 126, ISSN: 0000790750
BIOORGANIC & MEDICINAL CHEMISTRY, vol. 4, no. 1, JPNX007035329, January 1996 (1996-01-01), pages 49 - 53, ISSN: 0000869052
JOURNAL OF CHRONIC DISEASES, vol. 16, JPNX007035335, 1963, pages 335 - 342, ISSN: 0000869058
SKIN PHARMACOLOGY, vol. 7, no. 4, JPNX007035330, 1994, pages 188 - 200, ISSN: 0000869053
JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 47, no. 3, JPNX007035336, 1966, pages 235 - 246, ISSN: 0000869059
ADVANCES IN BIOLOGY OF SKIN, vol. 8, JPNX007035331, 1967, pages 421 - 445, ISSN: 0000869054
薬学雑誌, vol. 77, JPNX007035332, 1957, pages 1121 - 1123, ISSN: 0000869055
NEW FOOD INDUSTRY, vol. 27, no. 8, JPNX007035333, 1985, pages 77 - 84, ISSN: 0000869056
BULLETIN OF TOKYO GAKUGEI UNIVERSITY SER.IV, vol. 32, JPNX007035334, 1980, pages 121 - 126, ISSN: 0000869057
JOURNAL OF CHRONIC DISEASES, vol. 16, JPN4006023153, 1963, pages 335 - 342, ISSN: 0000790751
JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 47, no. 3, JPN4006023154, 1966, pages 235 - 246, ISSN: 0000790752

中村 稔 （外７名）

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