MAJOR HISTOCOMPATIBILITY COMPLEX SINGLE NUCLEOTIDE POLYMORPHISMS

Title:

MAJOR HISTOCOMPATIBILITY COMPLEX SINGLE NUCLEOTIDE POLYMORPHISMS

Document Type and Number:

Japanese Patent JP2023116700

Kind Code:

A

Abstract:

To provide a method for identification of single nucleotide polymorphisms (SNPs) that can be used for matching transplant donors and recipients and determining disease susceptibility.SOLUTION: A method of identifying a transplant donor for a recipient in need of a transplant comprises the following steps: a) determining the presence of one or more single nucleotide polymorphism alleles in the major histocompatibility complex (MHC) gamma block of the recipient in need of a transplant; b) determining the presence of one or more single nucleotide polymorphism alleles in the MHC gamma block of one or more potential transplant donors; and c) identifying a transplant donor based on the presence of one or more single nucleotide polymorphism alleles in the MHC gamma block of both the transplant donor and the recipient in need of a transplant.SELECTED DRAWING: None

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Inventors:

DAVID CHARLES SAYER
HAYLEY MARIANNE HOGAN
KAROLINA MERCOULIA

Application Number:

JP2023098088A

Publication Date:

August 22, 2023

Filing Date:

June 14, 2023

Export Citation:

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Assignee:

ILLUMINA INC

International Classes:

C12Q1/6827; C12Q1/6806; C12Q1/6837; C12Q1/6844; C12Q1/686; C12Q1/6869; C12Q1/6881

Attorney, Agent or Firm:

Mitsuyoshi Kamada
Hajime Takashima
Kyoko Doi
Yaeko Tamura
Hirofumi Taima
Atsuko Akai
Tomiya Tosaki
Soichi Ogou

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