Title:
MANUFACTURE OF 4-QUINOLINONES
Document Type and Number:
Japanese Patent JPS6087266
Kind Code:
A
Abstract:
1,2,3,4-Tetrahydro-4-quinolinones of the formula (I) are prepared from a 3-anilinopropionic acid of general for formula (II) which is treated successively with phosgene, with a base or by heating, and then with a Lewis acid or a strong acid. In the formulae (I) and (II), R denotes a hydrogen atom, a halogen atom, an alkyl radical (1 to 4 carbon atoms) or an alkoxy radical (1 to 4 carbon atoms), and R1 denotes a hydrogen atom or any alkyl radical (1 to 4 carbon atoms). The compounds of formula I are useful as intermediates in the production of known drugs.
Inventors:
MISHIERU ARUNOO
JIYANNPIEERU KORUBE
JIYANNPIEERU KORUBE
Application Number:
JP19586384A
Publication Date:
May 16, 1985
Filing Date:
September 20, 1984
Export Citation:
Assignee:
RHONE POULENC SANTE
International Classes:
C07D215/233; C07D215/26; C07D215/22; C07D265/06; (IPC1-7): C07D215/22; C07D215/26
Attorney, Agent or Firm:
Heiyoshi Odashima