Title:
マノオールの製造
Document Type and Number:
Japanese Patent JP6856553
Kind Code:
B2
Abstract:
Provided herein are methods of producing (+)-manool comprising: contacting geranylgeranyl diphosphate with an copalyl diphosphate (CPP) synthase to form a (9S, 10S)-copalyl diphosphate wherein the CPP synthase comprises an amino acid sequence having at least 90%, 95%, 98%, 99% and 100% sequence identity to a polypeptide selected from the group consisting of SEQ ID NO: 1 and SEQ ID NO:2; and contacting the CPP with a sclareol synthase enzyme to form (+)-manool.
Inventors:
Michelle Schalk
Letizia Roch
Letizia Roch
Application Number:
JP2017568149A
Publication Date:
April 07, 2021
Filing Date:
June 30, 2016
Export Citation:
Assignee:
Firmenich SA
International Classes:
C12N15/63; C07C27/02; C07C29/00; C07C33/05; C07C45/27; C07C47/225; C07C49/21; C07C67/14; C07C67/293; C07C69/145; C12N1/19; C12N1/21; C12N5/10; C12N15/52; C12P7/02; C12P7/40
Foreign References:
| WO2014022434A1 | ||||
| CN101319220A |
Other References:
ANNE CANIARD,BMC PLANT BIOLOGY,2012年 7月26日,Vol.112, No.119,p.1-13,URL,http://dx.doi.org/10.1186/1471-2229-12-119
Attorney, Agent or Firm:
Einzel Felix-Reinhard
Morita Taku
Junichi Maekawa
Hiroyasu Ninomiya
Ueshima
Morita Taku
Junichi Maekawa
Hiroyasu Ninomiya
Ueshima