Title:
MANUFACTURE OF OPTICALLY ACTIVE CYCLOPROPANE CARBOXYLIC ACID
Document Type and Number:
Japanese Patent JPS59134747
Kind Code:
A
Abstract:
The invention relates to a process for the preparation of enantiomers of trans vinyl-cyclopropane carboxylic acids of the formula I, wherein R is a methyl group or chlorine atom, by resolution of racemic trans compound or mixture of racemic cis and trans compounds by using (+)- or (-)-N-(1-formamido-2,2,2-trichloroethyl)-piperazine as a resolving agent in a polar solvent then separating the crystallizing salt of (+)-trans carboxylic acid and (-)-resolving agent or (-)-trans carboxylic acid and (+)-resolving agent from the mother liquor by filtration and obtaining the enantiomers by acidifying the mother liquor or the salts suspended in water followed by extraction with a solvent and evaporation. The products so obtained may be used as starting materials for the preparation of insecticides.
Inventors:
EREMEERU FUOGATSUSHIYU
RAASUROO TOEEKE
FUERENTSU FUAIGURU
RUDORUFU SOOSHIYU
YOOJIEFU BOZAAI
REJIYUOO KORUTA
YOOJIEFU NEMESHIYU
PEETERU BENCHIITSUKU
RAASUROO TOEEKE
FUERENTSU FUAIGURU
RUDORUFU SOOSHIYU
YOOJIEFU BOZAAI
REJIYUOO KORUTA
YOOJIEFU NEMESHIYU
PEETERU BENCHIITSUKU
Application Number:
JP22085083A
Publication Date:
August 02, 1984
Filing Date:
November 25, 1983
Export Citation:
Assignee:
CHINOIN GYOGYSZER ES VEGYESZET
International Classes:
C07C61/37; C07B31/00; C07B57/00; C07C51/00; C07C51/487; C07C61/40; C07C67/00; (IPC1-7): C07B19/00; C07C51/487; C07C61/37; C07C61/40
Attorney, Agent or Firm:
Matsuhiro Masahiro