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Title:
キノリン置換カルボネート及びカルバメート誘導体の調製
Document Type and Number:
Japanese Patent JP5302291
Kind Code:
B2
Abstract:
The invention relates to a process for preparing carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or a substrate that can be reduced to obtain the same. €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒR 1 -CH=CHCH 2 OC(O)-X-R 2 €ƒ€ƒ€ƒ€ƒ€ƒ(I)

Inventors:
Michael S. Allin
Lamiya H. Premchiandran
Chew-Chiang Chi Yang
Stephen Condon
Jiyoung Jei Dematty
Stephen A King
Lawrence Koracowski
Sukuma mana
Paul J. Nichols
Hemant H. Patel
Subatsuyu R Patel
Daniel J. Prater
Eric Jay Stoner
Chiang-Foo Chi Taen
Stephen J. A. Bittenberger
Application Number:
JP2010267057A
Publication Date:
October 02, 2013
Filing Date:
November 30, 2010
Export Citation:
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Assignee:
ABBOTT LABORATORIES
International Classes:
C07D215/14; C07C68/06; C07D215/18; C07D401/12; C07H17/08; C07B61/00
Domestic Patent References:
JP10291981A
Other References:
HOULIHAN,F. et al,Phase transfer catalysis in the tert-butyloxycarbonylation of alcohols, phenols, enols, and thiols with di-tert-butyl dicarbonate. ,Can J Chem,1985年,Vol.63, No.1,p.153-162
Attorney, Agent or Firm:
Kawaguchi International Patent Office
Chihiro Watanabe
Katsuma Osaki