Title:
MANUFACTURE OF UREIDE DERIVATIVE
Document Type and Number:
Japanese Patent JPS60136568
Kind Code:
A
Abstract:
PROCEDURE FOR THE OBTAINING OF COMPOUNDS OF 3- (UREID AND THIOUREIDOCICLOHEXILAMINO) -PROPAN-1,2-DIOL, OF FORMULA (I) PREFERENTLY (S) CIS-1 - {- 4 - [[3- (2-CICLOPROPILMATOXIFENOXI) - 2-HYDROXY-PROPIL] -AMINO] -CYC OHEXYL} -2-INIDAZOLIDINONE OR A SALT THEREOF. CONSISTING IN THE APPLICATION OF A COMPOUND OF FORMULA (II) IN THE PRESENCE OF A CONDENSING AGENT, PREFERABLY BASIC AND AN ORGANIC BASE, AT A TEMPERATURE BETWEEN 0-150GC, UNDER A GAS PROTECTIVE ATMOSPHERE. DON A ELEVADO A 2 REPRESENTS AN AROMATIC, HETEROCICLICO OR CARBOCICLICO CYCLE, PREFERABLY FENILO SUBSTITUTED, R, HYDROGEN OR LOWER ALKYL, ALGENO AZU, R3 AND R4 INDEPENDENT ENTREO X1 AND X2 ONE IS HYDROGEN AND THE OTHER ACIL OR X1 TOGETHER WITH R1 OR X2 TOGETHER WITH R2 MEANS THE GROUP = C = X. OF APPLICATION AS ANTI-HYPERTENSIVE BETA BLOCKERS AND BETA RECEIVERS. *FORMULA* (Machine-translation by Google Translate, not legally binding)
Inventors:
RINKAAN HAABII WAANAA
Application Number:
JP24635684A
Publication Date:
July 20, 1985
Filing Date:
November 22, 1984
Export Citation:
Assignee:
CIBA GEIGY AG
International Classes:
C07D233/30; A61K31/17; A61K31/415; A61K31/4166; A61K31/425; A61K31/44; A61K31/4427; A61K31/455; A61K31/47; A61K31/535; A61P9/08; A61P9/10; A61P9/12; A61P25/00; A61P25/02; A61P27/02; A61P27/06; C07C67/00; C07C239/00; C07C325/00; C07C335/14; C07D207/00; C07D209/00; C07D213/00; C07D215/00; C07D233/00; C07D233/28; C07D233/32; C07D233/34; C07D233/36; C07D285/00; C07D285/10; C07D295/14; C07D401/12; C07D403/12; C07D413/12; C07D417/12; C07C; C07D; (IPC1-7): A61K31/415; A61K31/425; A61K31/44; A61K31/455; A61K31/47; A61K31/535; C07C127/19; C07C157/09; C07D207/00; C07D209/00; C07D213/00; C07D215/00; C07D233/00; C07D233/30; C07D285/00; C07D401/12; C07D403/12; C07D417/12
Attorney, Agent or Firm:
Aoki Akira