To provide a method for manufacturing a 1-bromo-3,5-substituted benzene without using carbon tetrachloride.

The 1-bromo-3,5-substituted benzene is manufactured by allowing a compound represented by formula (1) to react with bromine in the presence of an iron halide in a monohalogenated hydrocarbon (for example, n-butyl chloride). In the formula, R¹ and R² are each independently a 1-12C alkyl group or a 3-12C cycloalkyl group, and R³, R⁴ and R⁵ are each independently a 1-6C alkyl group.