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Title:
MANUFACTURING METHOD OF CEPHALOSPORIN COMPOUND
Document Type and Number:
Japanese Patent JP2006096679
Kind Code:
A
Abstract:

To provide a new inexpensive manufacturing method of cefditoren.

The manufacturing method of 7-[2-methoxyimino-2-(2-aminothiazol-4-yl)acetamide]-3-[2-(4-methylthiazol-5-yl)vinyl]-3-cefem-4-carboxylic acid (cefditoren) represented by formula (I) comprises reacting a compound represented by formula (IV) [wherein R1 is a silyl protecting group; and R2 is a lower alkyl group or an aryl group] with a compound represented by formula (V).


Inventors:
ISHIYAMA TADASHI
OTA KAZUSANE
IKEDA SHINYA
MITOMO KOICHI
Application Number:
JP2004281626A
Publication Date:
April 13, 2006
Filing Date:
September 28, 2004
Export Citation:
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Assignee:
MEIJI SEIKA KAISHA
International Classes:
C07D501/24; C07F9/6547
Domestic Patent References:
JPH04327590A1992-11-17
JP2002234893A2002-08-23
JPH06247973A1994-09-06
JPH04327590A1992-11-17
JP2002234893A2002-08-23
JPH06247973A1994-09-06
Foreign References:
WO1998058932A11998-12-30
WO1998058932A11998-12-30