Title:
粥状硬化性動脈硬化のマーカー因子と用途
Document Type and Number:
Japanese Patent JP5379616
Kind Code:
B2
Abstract:
A method is provided for diagnosing or predicting atherosclerosis with the use of, as indicators, markers (factors) that allow early detection and progression prediction of the disease and a method for evaluating preventive or therapeutic effects. In one form, the present method includes detecting CD166 (ALCAM) level in a sample of a subject such as human. Another aspect of the present method includes evaluating preventive or therapeutic effects of a compound on atherosclerosis. A kit and an apparatus for carrying out such methods is also provided.
Inventors:
Yuji Kuge
Hiroko Hanzawa
Ken Sakamoto
Naomi Mari
Hiroko Hanzawa
Ken Sakamoto
Naomi Mari
Application Number:
JP2009208639A
Publication Date:
December 25, 2013
Filing Date:
September 09, 2009
Export Citation:
Assignee:
株式会社日立製作所
International Classes:
G01N33/68; G01N27/62; G01N33/15; G01N33/50; G01N33/53
Domestic Patent References:
| JP2001523956A |
Other References:
Rauch S et al.,Cholesterol-induced apoptosis is associated with downregulation of the activatedleukocyte cell adhesion molecule (ALCAM) in human monocytic cells,Naunyn-Schmiedeberg's Archives of Pharmacology,2009年 4月,Vol.. 379, Suppl. 1,pp. 42
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Satoshi Fujita