Title:
質量分析データ解析方法及び解析装置
Document Type and Number:
Japanese Patent JP5751126
Kind Code:
B2
Abstract:
Provided is a technique for accurately identifying a peptide even if the peptide cannot be identified by MS/MS ion search or de novo sequencing. The technique uses an MSn spectrum for a low m/z precursor ion. Such a spectrum contains a rather small amount of information, but this information is highly reliable when used for deducing an amino acid sequence by de novo sequencing. Accordingly, an MSn spectrum for a precursor ion having an m/z value of 500 or less is intentionally obtained, and de novo sequencing is performed on this spectrum to deduce the amino acid sequence covering the range from the m/z of the precursor ion and m/z=0. A highly reliable sequence tag can be generated from the deduced amino acid sequence, the m/z of the precursor ion of the MSn analysis, and the m/z of the precursor ion of the MS2 analysis.
Inventors:
Kentaro Morimoto
Application Number:
JP2011231435A
Publication Date:
July 22, 2015
Filing Date:
October 21, 2011
Export Citation:
Assignee:
SHIMADZU CORPORATION
International Classes:
G01N27/62; G16B40/10
Domestic Patent References:
| JP2007278712A | ||||
| JP2008145221A | ||||
| JP2006058111A |
Other References:
マトリックスサイエンス株式会社,蛋白質同定システム MASCOT ServerVersion 2.2 チュートリアル,2009年 3月,第21-22頁,URL: http://www.matrixscience.jp/pdf/jap_2.2_tutorial.pdf
Attorney, Agent or Firm:
Kyoto International Patent Office
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