Title:
MATERIAL AND METHOD FOR FILLING BONE VOID
Document Type and Number:
Japanese Patent JP2020089759
Kind Code:
A
Abstract:
To provide a material and a method for filling a bone void.SOLUTION: There are provided a material and a method for filling a bone void. A peptide comprising between about 7 amino acids and about 32 amino acids in a solution may be introduced to a target site. The peptide may undergo self-assembling under physiological conditions and/or in the presence of a cation. In one aspect, a method for filling a bone void in a subject is provided. The method includes the steps of: introducing a delivery device to a bone of a subject; positioning an end of the delivery device proximate a void in the bone where promotion of bone growth is desired; administering through the delivery device a solution comprising a self-assembling peptide comprising between about 7 and about 32 amino acids in an effective amount and in a concentration in a range of about 3 to about 5 w/v percent peptide to form a hydrogel scaffold under physiological conditions to promote bone growth at the target site; and removing the delivery device from the subject.SELECTED DRAWING: None
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Inventors:
LISA SPIRIO
GIL EUN SEOK
GIL EUN SEOK
Application Number:
JP2020036632A
Publication Date:
June 11, 2020
Filing Date:
March 04, 2020
Export Citation:
Assignee:
THREE D MATRIX KK
International Classes:
A61L27/22; A61L27/10; A61L27/36; A61L27/52; A61L27/54; A61L27/58; C12M1/00; C12M3/00
Domestic Patent References:
| JP2007105186A | 2007-04-26 | |||
| JP2010504972A | 2010-02-18 | |||
| JP2012082180A | 2012-04-26 | |||
| JP2008505919A | 2008-02-28 |
Foreign References:
| WO2010041636A1 | 2010-04-15 |
Attorney, Agent or Firm:
Takeshi Oshio