MEASUREMENT DEVICE BY SPECIFIC BINDING OF MAGNETIC PARTICLE

Title:

MEASUREMENT DEVICE BY SPECIFIC BINDING OF MAGNETIC PARTICLE

Document Type and Number:

Japanese Patent JP3239999

Kind Code:

B2

Abstract:

PROBLEM TO BE SOLVED: To measure a measured analytic object by allowing a separation reagent bound with magnetic particles to react with measured analytic object to form a complex, and moving the magnetic particle between receptacles by a mobile container to move a detection head.
SOLUTION: A well 2 is linearly placed in a plate 1, and a cylindrical sheath 4 is provided in a mobile container 3. The mobile container 3 possesses a pointed end at a conical body 6 at a lower end, a handle 7 controlling a vertical position at an upper end, and accommodates a movable pin 11 provided with a magnet 10 in a hole 9. When a inspected sample, magnetic particles 8, and the mobile container 3 are introduced into the well 2, the movable pin 11 is located at the upper part, and the magnetic particles 8 moves freely in the well 2. The measured analytic object reacts with a separation reagent having covered the magnet particles 8 to form an immune complex, and the mobile container 3 moves in the well 2 to promote mixing. After incubation, the magnetic particles 8 collect at the surface of the mobile container 3 to be transferred to the next well, and the particles are released and further aggregated for cleaning and tracer reaction, and the measurement needed is done in the last well.

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Inventors:

Yucca Tunanen

Application Number:

JP28410099A

Publication Date:

December 17, 2001

Filing Date:

February 01, 1994

Export Citation:

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Assignee:

Thermo Love Systems Osuke Yukiture

International Classes:

G01N33/543; G01N33/553; (IPC1-7): G01N33/543; G01N33/553

Domestic Patent References:

JP61107159A
JP62502708A

Other References:

【文献】国際公開87/5536(WO,A1)

Attorney, Agent or Firm:

Sota Asahina (1 person outside)

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