Title:
血液ガス中の一酸化窒素の測定およびそれに基づく処置
Document Type and Number:
Japanese Patent JP2005527834
Kind Code:
A
Abstract:
Nitric oxide is measured in blood as a marker of tissue blood flow and oxygenation. Where nitric oxide is measured to be below physiological or to be below average, in a patient having a disease associated with oxygen delivery deficiency, nitric oxide is infused alone or with nitrite. Where nitric oxide is measured to be normal, nitrite is infused. The storage time of whole blood or red blood cells is increased and the vasodilator response of outdated or NO depleted whole blood and red blood cells are increased by treatment with nitric oxide and/or nitrite. A patient in need of a transfusion is transfused with whole blood or red blood cells treated to increase vasodilator response therein.
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Inventors:
Stamlah, Jonathan S.
McMahon, Timothy Jay.
McMahon, Timothy Jay.
Application Number:
JP2004509410A
Publication Date:
September 15, 2005
Filing Date:
May 27, 2003
Export Citation:
Assignee:
Duke University
International Classes:
G01N33/49; A61M1/02; G01N33/84; (IPC1-7): G01N33/49; G01N33/84
Domestic Patent References:
| JP2002513400A | 2002-05-08 | |||
| JPH06510605A | 1994-11-24 | |||
| JP2001507789A | 2001-06-12 | |||
| JP2000509031A | 2000-07-18 | |||
| JPH11512436A | 1999-10-26 | |||
| JP2001507375A | 2001-06-05 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita