Title:
MEDICAL BASE MATERIAL PROVIDED WITH ANTITHROMBIC FUNCTION
Document Type and Number:
Japanese Patent JP3540457
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To stably impart an antithrombic function to a medical base material over a long period by fixing a compound containing a plurality of amidino groups or guanidino groups in a molecule as well as the prescribed number of aromatic rings to a base material surface by chemical bonding.
SOLUTION: A compound containing a plurality of amidino group or guanidino groups and one or more aromatic rings in a molecule is fixed to a base material surface by chemical bonding to form a medical base material. The compound may have a structure expressed by the formula, where R1 to R5 stand for hydrogen, a halogen atom or an alkyl group, and n stands for an integer of 0 or 1. Also, tris(4-amidinophenyl)1,3,5-benzenetricarboxylate trihydrochloride or the like may be used as the compound.
Inventors:
Masato Onishi
Hiromasa Obama
Tadahiro Motomura
Hiromasa Obama
Tadahiro Motomura
Application Number:
JP23237495A
Publication Date:
July 07, 2004
Filing Date:
September 11, 1995
Export Citation:
Assignee:
Terumo Corporation
International Classes:
A61L29/00; A61L33/00; (IPC1-7): A61L33/00; A61L29/00
Domestic Patent References:
| JP3504339A | ||||
| JP8333324A | ||||
| JP6023032A |
Other References:
Ian J. Reynolds,Studies on the effects of several pentamidine analogues on the NMDA receptor,European Journal of Pharmacology,1993年,244,175-179