Title:
【発明の名称】治療剤
Document Type and Number:
Japanese Patent JP2003503452
Kind Code:
A
Abstract:
Substituted cycloalkyl compounds with 3 to 6 carbon atoms in the ring, one carbon linked to each of two side groups R and R', and pharmaceutically acceptable salts thereof in which R is phenyl optionally substituted by one or more halo substituents or R is naphthyl; and R' is -[X-Y-S(O)m-Z-N-R1-R2], wherein X is carbonyl or a carbon directly linked to each of a hydroxyl group and R5 in which R5 is H or alkyl, Y is an alkylene chain optionally substituted by one or more alkyl groups, m can be 0, 1 or 2, Z is an alkylene chain containing 2 to 5 carbon atoms optionally substituted by one or more alkyl groups, and R1 and R2, which are the same or different, are H, alkyl, or arylalkyl, provided that when R1 is benzyl, R2 is H or methyl; have utility in the treatment of drug misuse or other addictive disorders.
Inventors:
Rascombe, Graham Paul
Patricia Leslie, Needham
Patricia Leslie, Needham
Application Number:
JP2001507472A
Publication Date:
January 28, 2003
Filing Date:
June 21, 2000
Export Citation:
Assignee:
Knorr GMBH
International Classes:
A61K31/131; A61K31/133; A61K31/145; A61P25/30; A61P25/32; A61P25/34; A61P25/36; A61P39/02; C07C317/28; C07C323/25; (IPC1-7): A61K31/131; A61K31/133; A61P25/30; A61P25/32; A61P25/34; A61P25/36; A61P39/02; C07C317/28; C07C323/25
Domestic Patent References:
| JPH06293759A | 1994-10-21 | |||
| JPH06293760A | 1994-10-21 |
Attorney, Agent or Firm:
Yoshio Kawaguchi (5 outside)