To provide a medical treatment apparatus and a method for producing it which can avoid a liquid polymer from being peeled off when a silicone oil or a fluid fluorinated polymer is used as a lubricant and reduces sliding resistance with a rubber piston or the like.

In the method for producing a medical treatment apparatus wherein a fluorine-containing layer is formed on the medical liquid contacting surface, a liquid fluorinated polymer is coated over the medical treatment apparatus wherein at least a fluorine-containing layer fixed on the medical liquid contacting surface is formed and at least one of the medical liquid contacting surface of the medical treatment apparatus, and then processed with plasma.